The series depicts about the family of Frank Gallagher, who is a drug addicted single father of six children.
But in January 2018, the actress took to social media to announce that her time on the show was finishing up.
I mean I had the swine flu or something, it was terribly bad so I just chugged some Day-Quil.
Karen has a new boyfriend and he's a lot older than she is.
I knew it from the second I read the pilot script, this was different, this was special.
But moving parts are inevitable in a program with such a long lifespan, and over time, series regulars and fan favorites have found reason to depart or return to the comforts or discomforts of the show's South Side of Chicago setting.